Just one person's opinion: We need to get runners from right side to right side without having to make a sharp turn that would slow them down.
One excellent way, when available, is to specify that they must run to the end of a yellow line on one street and then run to the right of the yellow line on the street they have turned onto.
Usually it is tough to actually put cones in a curve in these situations, because you would be blocking traffic in the other lanes. So the runners can run a curved path or a straight path, as they choose, to run to the outside of these "control points".
If one or both of the roads have median islands, I think you have runners run around the end of the islands. If you have to get runners out of and back into the right hand curb lanes, you need to choose a control point where runners can leave that curb lane, and also specify a point where they have to be into the curb lane of the 2nd street. In other words, design the restrictions so that it's possible to run somewhat of a rounded turn-- when possible. It's good to make these points super-easy to locate-- like "even with light pole/end of storm drain/etc". Sometimes I use "before the (2nd, or ?) hash mark between curb lane and next lane. With that one and all such control points, good idea to give a distance in feet relative to the end of the median strip.